2-脱氧-D-葡萄糖, 98%
| 【编号】：109194 【产品名称】：2-脱氧-D-葡萄糖, 98% 【规格】：1g 【用途】：   2-脱氧-D-葡萄糖, 98%
Product Name： 2-Deoxy-D-glucose
别名：2-脱氧-D-葡萄糖 ;2-去氧-D-葡萄糖,D-2-脱氧葡萄糖
CAS号：154-17-6
分子式：C6H12O5
分子量：164.16
介绍： 溶于水和乙醇。
用途： 2-脱氧-D-葡萄糖（2-Deoxy-D-Glucose，2-DG）为天然抗代谢物类抗生素，具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。
熔点： 146-147 °C
特定比重： 1.533
比旋光度： 46.5 ° (C=1, H2O)
贮存： 储存温度2-8℃
生化和生理学机理： 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPKwww.atcc360.com
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