阿齐沙坦, ≥98% (HPLC)
【编号】:122333 【产品名称】:阿齐沙坦, ≥98% (HPLC) 【规格】:10mg 【用途】: 阿齐沙坦, ≥98% (HPLC)Product Name: AzilsartanCAS号: 147403-03-0 分子式: C25H20N4O5 分子量: 456.45 用途: 阿齐沙坦(又称阿齐沙坦酯,英语:Azilsartan)(INN) 是一款正处于研发中的治疗高血压症的血管紧张素II受体拮抗剂药物,多用于治疗高血压症,也是目前唯一处于末期临床的血管紧张素II受体拮抗剂(沙坦类)药物。 贮存:储存温度2-8°C 生化和生理学机理:Azilsartan is a highly potent and slowly dissociating Angiotensin II type 1 (AT1) receptor blocker (ARB) with an IC50 of 2.6 nM. It is the active form of Azilsartan medoxomil, used for treatment of hypertension. Azilsartan may also have potentially beneficial effects on metabolic syndrome including insulin sensitizing activity that may involve more than just blockade of AT(1) receptors. |
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