当前位置:对照品 > 实验试剂 > 生化试剂 >
LUF6000
  【编号】:L127479

  【产品名称】:LUF6000

  【规格】:5MG

  【用途】:

  LUF6000

  Product Name: LUF6000
  CAS号:890087-21-5
  分子式:C22H20Cl2N4
  分子量:411.33
  贮存: 储存温度-20°C
  可溶性: DMSO
  生化和生理学机理:
  LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR). LUF6000 was found to be an allosteric enhancer of Emax of structurally diverse agonists at the A3 AR, being more effective for low-Emax agonists than for high-Emax agonists. LUF6000 exerted an Emax-enhancing effect at a concentration of 0.1 microM or higher, and was shown to increase the Emax of Cl-IB-MECA and other low-efficacy agonists to a larger extent than that of the high-efficacy agonist NECA. Interestingly, LUF6000 converted a nucleoside A3 AR antagonist MRS542, but not a non-nucleoside antagonist MRS1220, into an agonist.
上一篇:Enzalutamide, ≥98% 下一篇:PF-2545920, ≥95%



    
    首 页 | 对照品| 标准品| 标准物质| 实验试剂| 培养基| 菌种购买| 新闻中心| 联系我们| 网站地图

    2011-2018 北京莱耀生物版权所有豫ICP备17046142号