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齐拉西酮
  【编号】:125730

  【产品名称】:齐拉西酮

  【规格】:10MG

  【用途】:

  齐拉西酮

  Product Name: Ziprasidone
  CAS号:146939-27-7
  分子式:C21H21ClN4OS
  分子量:412.94
  贮存: 储存温度-20°C
  可溶性: DMSO
  生化和生理学机理:
  Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.
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