普拉西坦,≥99%
【编号】:126924 【产品名称】:普拉西坦,≥99% 【规格】:50MG 【用途】: 普拉西坦,≥99%
Product Name: Pramiracetam
CAS号:68497-62-1
分子式:C14H27N3O2
分子量:269.38
贮存: 储存温度-20°C
可溶性:
DMSO 54 mg/mL
Water <1 mg/mL
Ethanol <1 mg/mL
生化和生理学机理:
Description:
IC50 Value: N/A
Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries.
in vitro: Pramiracetam sulfate did not exhibit any affinity in vitro for dopaminergic , GABAergic, serotoninergic, adrenergic, muscarinic, adenosine (IC50 > 10 uM), and benzodiazepine receptors (IC50 > 1 uM) binding sites [1].
in vivo: In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 400, 800, 1,200, and 1,600 mg oral doses of pramiracetam after an overnight fast. Mean (+/- SD) peak plasma concentrations of the four dose groups (2.71 +/- 0.54, 5.40 +/- 1.34, 6.13 +/- 0.71, 8.98 +/- 0.71 micrograms/mL) were attained between two to three hours following drug administration [2]. Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in a 16-arm radial maze in which nine arms were baited with food [3].
Toxicity: N/A
Clinical trial: N/A
|
上一篇:Preladenant, ≥98% | 下一篇:PF-04447943 |
---|
热销产品 新品上架