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普拉西坦,≥99%
  【编号】:126924

  【产品名称】:普拉西坦,≥99%

  【规格】:50MG

  【用途】:

  普拉西坦,≥99%

  Product Name: Pramiracetam
  CAS号:68497-62-1
  分子式:C14H27N3O2
  分子量:269.38
  贮存: 储存温度-20°C
  可溶性:
  DMSO 54 mg/mL
  Water <1 mg/mL
  Ethanol <1 mg/mL
  生化和生理学机理:
  Description:
  IC50 Value: N/A
  Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries.
  in vitro: Pramiracetam sulfate did not exhibit any affinity in vitro for dopaminergic , GABAergic, serotoninergic, adrenergic, muscarinic, adenosine (IC50 > 10 uM), and benzodiazepine receptors (IC50 > 1 uM) binding sites [1].
  in vivo: In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 400, 800, 1,200, and 1,600 mg oral doses of pramiracetam after an overnight fast. Mean (+/- SD) peak plasma concentrations of the four dose groups (2.71 +/- 0.54, 5.40 +/- 1.34, 6.13 +/- 0.71, 8.98 +/- 0.71 micrograms/mL) were attained between two to three hours following drug administration [2].  Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in a 16-arm radial maze in which nine arms were baited with food [3].
  Toxicity: N/A
  Clinical trial: N/A
上一篇:Preladenant, ≥98% 下一篇:PF-04447943



    
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